diff --git a/__tests__/cli.test.js b/__tests__/cli.test.js
index 5d434c37d..47c2bc57b 100644
--- a/__tests__/cli.test.js
+++ b/__tests__/cli.test.js
@@ -56,5 +56,17 @@ describe('cli', () => {
         expect(utils.writeFile.mock.calls[0][1]).toContain('.example')
       })
     })
+
+    it('compiles CSS file with autoprefixer', () => {
+      cli(['build', inputCssPath]).then(() => {
+        expect(process.stdout.write.mock.calls[0][0]).toContain('-ms-input-placeholder')
+      })
+    })
+
+    it('compiles CSS file without autoprefixer', () => {
+      cli(['build', inputCssPath, '--no-autoprefixer']).then(() => {
+        expect(process.stdout.write.mock.calls[0][0]).not.toContain('-ms-input-placeholder')
+      })
+    })
   })
 })
diff --git a/src/cli/commands/build.js b/src/cli/commands/build.js
index ab3939854..f94d51cde 100644
--- a/src/cli/commands/build.js
+++ b/src/cli/commands/build.js
@@ -22,11 +22,16 @@ export const options = [
     usage: '-c, --config <file>',
     description: 'Tailwind config file.',
   },
+  {
+    usage: '--no-autoprefixer',
+    description: "Don't add vendor prefixes using autoprefixer.",
+  },
 ]
 
 export const optionMap = {
   output: ['output', 'o'],
   config: ['config', 'c'],
+  noAutoprefixer: ['no-autoprefixer'],
 }
 
 /**
@@ -60,11 +65,11 @@ function stopWithHelp(...msgs) {
  * @param {string} outputFile
  * @return {Promise}
  */
-function build(inputFile, configFile, outputFile) {
+function build(inputFile, configFile, outputFile, autoprefix) {
   const css = utils.readFile(inputFile)
 
   return new Promise((resolve, reject) => {
-    postcss([tailwind(configFile), autoprefixer])
+    postcss([tailwind(configFile)].concat(autoprefix ? [autoprefixer] : []))
       .process(css, {
         from: inputFile,
         to: outputFile,
@@ -82,8 +87,10 @@ function build(inputFile, configFile, outputFile) {
  * @param {string} outputFile
  * @return {Promise}
  */
-function buildToStdout(inputFile, configFile, outputFile) {
-  return build(inputFile, configFile, outputFile).then(result => process.stdout.write(result.css))
+function buildToStdout(inputFile, configFile, outputFile, autoprefix) {
+  return build(inputFile, configFile, outputFile, autoprefix).then(result =>
+    process.stdout.write(result.css)
+  )
 }
 
 /**
@@ -95,12 +102,12 @@ function buildToStdout(inputFile, configFile, outputFile) {
  * @param {int[]} startTime
  * @return {Promise}
  */
-function buildToFile(inputFile, configFile, outputFile, startTime) {
+function buildToFile(inputFile, configFile, outputFile, autoprefix, startTime) {
   utils.header()
   utils.log()
   utils.log(emoji.go, 'Building...', chalk.bold.cyan(inputFile))
 
-  return build(inputFile, configFile, outputFile).then(result => {
+  return build(inputFile, configFile, outputFile, autoprefix).then(result => {
     utils.writeFile(outputFile, result.css)
 
     const prettyTime = prettyHrtime(process.hrtime(startTime))
@@ -126,6 +133,7 @@ export function run(cliParams, cliOptions) {
     const inputFile = cliParams[0]
     const configFile = cliOptions.config && cliOptions.config[0]
     const outputFile = cliOptions.output && cliOptions.output[0]
+    const autoprefix = !cliOptions.noAutoprefixer
 
     !inputFile && stopWithHelp('CSS file is required.')
     !utils.exists(inputFile) && stop(chalk.bold.magenta(inputFile), 'does not exist.')
@@ -135,8 +143,8 @@ export function run(cliParams, cliOptions) {
       stop(chalk.bold.magenta(configFile), 'does not exist.')
 
     const buildPromise = outputFile
-      ? buildToFile(inputFile, configFile, outputFile, startTime)
-      : buildToStdout(inputFile, configFile, outputFile)
+      ? buildToFile(inputFile, configFile, outputFile, autoprefix, startTime)
+      : buildToStdout(inputFile, configFile, outputFile, autoprefix)
 
     buildPromise.then(resolve).catch(reject)
   })