diff --git a/packages/grpc-js/src/xds-client.ts b/packages/grpc-js/src/xds-client.ts
index 732858a3..80d19e0e 100644
--- a/packages/grpc-js/src/xds-client.ts
+++ b/packages/grpc-js/src/xds-client.ts
@@ -62,11 +62,12 @@ function loadAdsProtos(): Promise<adsTypes.ProtoGrpcType> {
         defaults: true,
         oneofs: true,
         includeDirs: [
-          'deps/envoy-api/',
-          'deps/udpa/',
-          'node_modules/protobufjs/',
-          'deps/googleapis/',
-          'deps/protoc-gen-validate/',
+          // Paths are relative to src/build
+          __dirname + '/../../deps/envoy-api/',
+          __dirname + '/../../deps/udpa/',
+          __dirname + '/../../node_modules/protobufjs/',
+          __dirname + '/../../deps/googleapis/',
+          __dirname + '/../../deps/protoc-gen-validate/',
         ],
       }
     )